Intriguing Federal Legislation Introduced Regarding Breast Density Masking Breast Cancer
Approximately 10 million women have high breast density in the United States and there is currently no FDA-approved treatment for this condition. For more information about breast density please visit www.areyoudense.org. On October 25, 2017, new federal legislation was introduced in both the House (H.R. 4122) by Representative Rosa L. DeLauro (D-Conn) and in the Senate (S. 2006) by Senator Dianne Feinstein (D-Cal) with regard to how we are dealing with the issues around breast density and how it relates to breast cancer. The parallel bills mandate that mammography reports provided to patients and physicians include a summary that (i) includes information about breast density; (ii) conveys information about the effect of breast density in masking the presence of breast cancer on mammography; and (iii) communicates that individuals with dense breasts should talk with their health care providers about the summary and the potential benefit of additional testing. Additionally, the bills require that the Department of Health and Human Services expand and intensify programs and activities for research relating to breast density. The bills have been referred to the House Committee on Health and Commerce and the Senate Committee on Energy and the Senate Committee on Health, Education, Labor and Pensions.
President and CEO of Seattle, WA based Atossa Genetics (NasdaqCM: ATOS), Dr. Steven Quay, commented on this subject, “The presence of dense breast tissue can make it more difficult to evaluate the results of a mammogram because dense breast tissue is comprised of less fat and more stromal tissue which appears white on a mammogram. Cancer also appears white and tumors are therefore often hidden or masked by the dense tissue. Breast density is also associated with an increased risk of breast cancer. Although numerous states have recently enacted laws requiring that patients be notified of breast density, there is no federal standard and approximately 20 states still do not require that information about density be conveyed to the patient. We believe woman have the right to receive this important health information and we applaud the pending federal legislation. In addition, the provisions in the legislation that require expansion of programs and research activities related to breast density should improve diagnosis capabilities and accelerate treatments for this major breast cancer risk factor; which is one of only a few risk factors that can actually be modified.” Atossa is developing the drug Endoxifen for tamoxifen-refractory breast cancer patients, the treatment of mammographic breast density and other breast conditions. Atossa’s proprietary Endoxifen is being developed as an oral form as well as a topical solution, like a lotion, that can be applied directly to the breast. Atossa recently completed a Phase 1 study of its oral and topical Endoxifen and reported that all objectives of that study were successfully met. A Phase 2 study will be conducted at Stockholm South General Hospital in Sweden and will be led by principal investigator Dr. Per Hall, M.D., Ph.D., Head of the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet.
To learn about the interesting work that Seattle, WA based biotech firm Atossa Genetics (NasdaqGM: ATOS) is doing in breast cancer treatment please visit the Vista Partners Company Dedicated Page.